Datuk Henrynus Amin was born on 22 February 1959 in Kg Marakau, Ranau. He is married to Esther Lee Nyut Yun and they have 4 children.

Henrynus is currently the Secretary General of the Sabah United Party (Parti Bersatu Sabah) and a member of the Party's Political Bureau. He is a graduate in political science, having obtained an M.A. (Political Science) from Southern Illinois University, Carbondale, USA.

He has a varied working background in government and politics. Aside from working as a civil servant for many years, Mr. Amin also served as a researcher with the Sabah Institute for Development Studies (IDS).

He joined active politics through PBS in 1987 and served as Political Secretary in the Prime Minister's Department in Kuala Lumpur May 1987 until December 1989. Subsequently he also worked as Political Secretary to the Chief Minister of Sabah from December 1989 until January 1984.

Datuk Henrynus worked briefly as the Special Officer (Parliamentary Affairs) to the Hon. Minister of Science, Technology and Innovation from May 2008 until December 2008.

Datuk Henrynus served as the Member of Parliament (MP) for the Kinabalu constituency from 1995 until 1999. He is a Life Member of the Kadazandusun Cultural Association (KDCA) since 1998. For his numerous contributions to the state, he was awarded the Ahli Darjah Kinabalu (ADK) in 1989 by the TYT Yang diPertua Negeri Sabah.

On 5th June 2010, Datuk Henrynus was conferred the "Panglima Jasa Negara (PJN)" which carries the title "Datuk" by the Seri Paduka Baginda Yang DiPertuan Agong.